解剖学和形态学
麻醉学
听力与言语-语言病理学
行为科学
心脏和心血管系统
细胞和组织工程学
临床神经病学
危重症监护医学
牙科,口腔外科和医学
皮肤病学
急诊医学
内分泌学和新陈代谢
肠胃学和肝脏学
老人病学和老年医学
卫生保健科学和服务
血液学
免疫学
传染病
综合和补充性医学
医学伦理学
医学信息学
医学实验室技术
医学,全科和内科
医学,法律
医学,研究和试验
神经系统科学
护理
营养学和饮食学
产科医学和妇科医学
肿瘤学
眼科学
整形外科学
耳鼻喉科学
病理学
儿科学
周围血管疾病
药理学和药剂学
生理学
基本医疗保健
精神病学
公共、环境和职业卫生
放射学,核医学和医学成像
康复学
生殖生物学
呼吸系统
风湿病学
运动科学
外科学
毒理学
热带医学
泌尿学和肾脏学
病毒学
老年医学
健康政策和服务
心理学,临床
abstract:BACKGROUND:The goal of this study was to compare development of emotional symptomatology during smoking cessation with transdermal nicotine patches in subjects with and without a history of depression. METHODS:Twenty-five subjects, 14 with a history of depression and 11 without such a history, were evaluated before be...
journal_title:Journal of affective disorders
pub_type: 杂志文章
doi:10.1016/s0165-0327(01)00468-2
更新日期:2002-11-01 00:00:00
abstract:OBJECTIVE:To investigate the reported association between low vitamin E levels and depressive symptoms in a population-based study. METHODS:The study is based on a cohort of 3884 adults aged 60 years and over who participated in the third survey of the Rotterdam Study, were screened for depressive symptoms with the Ce...
journal_title:Journal of affective disorders
pub_type: 杂志文章
doi:10.1016/s0165-0327(01)00427-x
更新日期:2002-10-01 00:00:00
abstract:BACKGROUND:Previous findings of P300 alterations in depressive disorder have been controversial. We therefore used multivariate methods to study the relationship between P300 and affective and psychotic symptoms in depressive disorder. METHODS:The P300 of 22 psychotropic drug-free depressed out-patients was registered...
journal_title:Journal of affective disorders
pub_type: 杂志文章
doi:10.1016/s0165-0327(01)00410-4
更新日期:2002-09-01 00:00:00
abstract::There is good evidence to suggest that depression is highly correlated with perceptions of low rank and subordinate status (i.e. feeling inferior, low-self esteem, feeling that others look down on the self, and submissive behaviour). However, it is possible for people to feel inferior and anxious, and behave submissiv...
journal_title:Journal of affective disorders
pub_type: 杂志文章
doi:10.1016/s0165-0327(01)00392-5
更新日期:2002-09-01 00:00:00
abstract:BACKGROUND:The authors compared the effect of clonazepam supplement treatment on unipolar depression and bipolar depression. METHODS:A total of 38 protracted depression patients with unipolar depression (n = 19) or bipolar depression (n = 19) were treated with 3.0 mg clonazepam for 4 weeks. RESULTS:In the unipolar de...
journal_title:Journal of affective disorders
pub_type: 杂志文章
doi:10.1016/s0165-0327(01)00358-5
更新日期:2002-09-01 00:00:00
abstract::We examined 180 patients with a principal diagnosis of Major Depression, with or without a lifetime diagnosis of alcohol dependence. In the ever-dependent group, the GAF was lower; cannabis dependence higher; and Borderline, Schizotypal and Paranoid personality disorders more common. They reported more paranoia and in...
journal_title:Journal of affective disorders
pub_type: 杂志文章
doi:10.1016/s0165-0327(01)00365-2
更新日期:2002-08-01 00:00:00
abstract:BACKGROUND:We evaluated the cognitive profile of 48 patients with major depression following their first myocardial infarction (MI). METHODS:The cognitive performance of the patients was compared with the performance of 48 non-depressed MI patients and 48 healthy controls. RESULTS:Depressed MI patients performed slow...
journal_title:Journal of affective disorders
pub_type: 杂志文章
doi:10.1016/s0165-0327(01)00348-2
更新日期:2002-07-01 00:00:00
abstract:BACKGROUND:Depression is the most common psychiatric disorder in deliberate self-harm (DSH) patients and in those who commit suicide. The aim of this study was to examine the treatment received by DSH patients with depression and their progress following DSH. METHODS:A representative sample of 106 patients with an ICD...
journal_title:Journal of affective disorders
pub_type: 杂志文章
doi:10.1016/s0165-0327(01)00317-2
更新日期:2002-06-01 00:00:00
abstract:BACKGROUND:The influence of seasons on mood disorders is controversial. OBJECTIVE:To examine monthly variations in admissions for mania and depressions including variations with sex and age and correlations with frequencies of suicides. METHODS:All admissions for mania or depression (N=4341) in a population of 1,800,...
journal_title:Journal of affective disorders
pub_type: 杂志文章
doi:10.1016/s0165-0327(00)00373-6
更新日期:2002-05-01 00:00:00
abstract:BACKGROUND:Body dysmorphic disorder (BDD) is a distressing and impairing preoccupation with an imagined or slight defect in appearance, with depression as its most frequent comorbid condition. The purpose of this study was to evaluate the rate of BDD in a cohort of consecutive outpatients with typical and atypical majo...
journal_title:Journal of affective disorders
pub_type: 杂志文章
doi:10.1016/s0165-0327(01)00304-4
更新日期:2002-05-01 00:00:00
abstract:BACKGROUND:It has been established that depressed patients manifest a higher risk of committing suicide. The role of delusional experiences accompanying depressive symptomatology as a risk factor for suicidal behaviour has been investigated but the results are inconsistent. METHOD:In the present study, 40 elderly depr...
journal_title:Journal of affective disorders
pub_type: 杂志文章
doi:10.1016/s0165-0327(00)00322-0
更新日期:2002-05-01 00:00:00
abstract::Background. Social phobia has been under-recognised and under-treated in many countries. Little is known about its economic impact. This study aimed to identify the economic consequences of social phobia for individuals, health services and wider society. Methods. Secondary analysis of 1993-1994 Psychiatric Morbidity ...
journal_title:Journal of affective disorders
pub_type: 杂志文章
doi:10.1016/s0165-0327(00)00323-2
更新日期:2002-04-01 00:00:00
abstract::We measured plasma free HVA and MHPG in 39 cases of psychosis or mania judged to be caused by antidepressant exacerbation of symptoms. A total of 24 of patients had been receiving selective serotonin reuptake inhibitors (SSRI's). The SSRI group showed a pattern of increased plasma HVA similar to a comparison group of ...
journal_title:Journal of affective disorders
pub_type: 杂志文章
doi:10.1016/s0165-0327(00)00327-x
更新日期:2002-04-01 00:00:00
abstract:BACKGROUND:Epidemiological and clinical studies have reported the frequent co-occurrence of social phobia (SP) and alcohol use disorders. Patients with SP often use alcohol to cope with the social situations they fear, and to lessen anticipatory anxiety, behavioral inhibition, and phobic avoidance. We investigated whet...
journal_title:Journal of affective disorders
pub_type: 杂志文章
doi:10.1016/s0165-0327(00)00316-5
更新日期:2002-02-01 00:00:00
abstract::The paper reviews briefly and comments in detail on selected events in the history of lithium treatment. The events include Cade's discovery of lithium's antimanic action, the discovery and establishment of its prophylactic action, the ensuing debate, amelioration and prevention of side effects and risks, use during p...
journal_title:Journal of affective disorders
pub_type: 历史文章,杂志文章,评审
doi:10.1016/s0165-0327(01)00380-9
更新日期:2001-12-01 00:00:00
abstract:BACKGROUND:The present analysis was performed on data from a subsample of patients with schizoaffective disorder, bipolar type, who participated in a multicenter, double-blind study comparing olanzapine to haloperidol. METHODS:Patients with schizoaffective disorder bipolar type, characterized as currently manic, mixed...
journal_title:Journal of affective disorders
pub_type: 临床试验,杂志文章,多中心研究,随机对照试验
doi:10.1016/s0165-0327(00)00303-7
更新日期:2001-12-01 00:00:00
abstract:BACKGROUND:There have been few systematic studies of the treatment of bipolar II depression. While divalproex sodium (DVPX) is effective in acute mania, there are few data on the antidepressant effects of DVPX. Similarly, little is known regarding the use of DVPX administered in a single daily dose. METHOD:We performe...
journal_title:Journal of affective disorders
pub_type: 临床试验,杂志文章
doi:10.1016/s0165-0327(01)00434-7
更新日期:2001-12-01 00:00:00
abstract:BACKGROUND:The use of college students with high scores on a depression rating scale as analogues for depression by psychological researchers has generated controversy. Critics of analogue research argue that depression is qualitatively different in analogue and clinical samples. OBJECTIVE:To conduct a further compari...
journal_title:Journal of affective disorders
pub_type: 杂志文章
doi:10.1016/s0165-0327(00)00305-0
更新日期:2001-10-01 00:00:00
abstract:PURPOSE:To analyze whether affective symptoms during psychiatric treatment in childhood or adolescence could predict the later development of depressive symptoms. METHOD:We used a "catch-up" design. A cohort of former child and adolescent psychiatric patients was assessed in adulthood with standardized instruments acc...
journal_title:Journal of affective disorders
pub_type: 杂志文章
doi:10.1016/s0165-0327(00)00302-5
更新日期:2001-10-01 00:00:00
abstract:OBJECTIVE:This research investigated the impact of adolescent onset bipolar illness on perceived family functioning in stabilized bipolar I (B) and unipolar (U) probands, and normal controls (C). METHOD:Sample N=119: 44 bipolar 1(17 M, 27 F), 30 unipolar (9 M, 21 F), and 45 controls (19 M, 26 F). Mean ages: 19.9, 18.5...
journal_title:Journal of affective disorders
pub_type: 杂志文章
doi:10.1016/s0165-0327(00)00281-0
更新日期:2001-09-01 00:00:00
abstract:BACKGROUND:Optimal long-term treatment of major depression should assess the background factors affecting remission and recurrent episodes. The duration and number of previous depressive episodes has been shown to be important for recurrence. This long-term prospective study of patients with major depression assessed t...
journal_title:Journal of affective disorders
pub_type: 杂志文章
doi:10.1016/s0165-0327(00)00260-3
更新日期:2001-08-01 00:00:00
abstract:OBJECTIVE:To determine if gabapentin is effective in monotherapy or add-on treatment of non-refractory bipolar disorder in open prospective treatment. METHODS:Charts of 21 outpatients meeting DSM-IV criteria for bipolar spectrum disorder (type I, type II, NOS, and cyclothymia) and who were treated with gabapentin were...
journal_title:Journal of affective disorders
pub_type: 杂志文章
doi:10.1016/s0165-0327(00)00218-4
更新日期:2001-07-01 00:00:00
abstract:STUDY OBJECTIVE:The aim of this preliminary study is to investigate the regional blood flow in response to ECT (electroconvulsive therapy) and to identify any responsive-pattern to the treatment. METHODS: STUDY DESIGN:Single longitudinal prospective study of cohorts. SUBJECTS:For this preliminary study ten patients,...
journal_title:Journal of affective disorders
pub_type: 杂志文章
doi:10.1016/s0165-0327(00)00200-7
更新日期:2001-06-01 00:00:00
abstract:BACKGROUND:We investigated whether melancholic and non-melancholic Japanese depressive patients differed in regard to a personality feature, interpersonal sensitivity, as measured by the Interpersonal Sensitivity Measure (IPSM). METHODS:In addition to 154 normal controls, 66 remitted melancholic patients and 55 remitt...
journal_title:Journal of affective disorders
pub_type: 杂志文章
doi:10.1016/s0165-0327(00)00222-6
更新日期:2001-05-01 00:00:00
abstract:BACKGROUND:Depression is the most prevalent psychiatric disorder in the elderly and several studies indicate that 10-15% of persons over 65 years suffer from significant depressive symptoms. Despite the high prevalence, most cases of depression in the elderly remain unrecognized and untreated, maybe because of a differ...
journal_title:Journal of affective disorders
pub_type: 杂志文章
doi:10.1016/s0165-0327(00)00245-7
更新日期:2001-05-01 00:00:00
abstract:BACKGROUND:The psychological literature concerned with the aetiology and maintenance of depression has generally been considered too diverse to allow for integration of concepts into a single comprehensive review. Moreover, there is little understanding of the original theorists' conceptualisation of the key themes und...
journal_title:Journal of affective disorders
pub_type: 杂志文章,评审
doi:10.1016/s0165-0327(00)00204-4
更新日期:2001-04-01 00:00:00
abstract:INTRODUCTION:Subsyndromal depression has been associated with an increased risk of the development of major depressive disorder (MDD). Since treatment trials of adolescent MDD often result in subsyndromal depression as the outcome, the long-term course of these youth would be useful to understand. METHODS:107 adolesce...
journal_title:Journal of affective disorders
pub_type: 临床试验,杂志文章
doi:10.1016/s0165-0327(00)00189-0
更新日期:2001-03-01 00:00:00
abstract:BACKGROUND:Quantitative EEG studies have identified a number of sleep abnormalities in adults with major depressive disorders (MDD), including a reduction in the amplitude of delta activity during NREM sleep. To date, these methodologies have not been used in early onset MDD. METHODS:Delta activity during NREM sleep w...
journal_title:Journal of affective disorders
pub_type: 杂志文章
doi:10.1016/s0165-0327(00)00194-4
更新日期:2001-03-01 00:00:00
abstract:BACKGROUND:Although prison inmates are reported to exhibit elevated rates of depressive disorders, little is known about anti-depressant prescribing patterns in correctional institutions. METHODS:The study population consisted of 5305 Texas Department of Criminal Justice (TDCJ) inmates who were diagnosed with one of t...
journal_title:Journal of affective disorders
pub_type: 杂志文章
doi:10.1016/s0165-0327(00)00188-9
更新日期:2001-03-01 00:00:00
abstract:BACKGROUND:Bright artificial light improves non-seasonal depression. Preliminary observations suggest that sunlight could share this effect. METHODS:Length of hospitalization was recorded for a sample of 415 unipolar and 187 bipolar depressed inpatients, assigned to rooms with eastern (E) or western (W) windows. RESU...
journal_title:Journal of affective disorders
pub_type: 杂志文章
doi:10.1016/s0165-0327(00)00149-x
更新日期:2001-02-01 00:00:00
abstract::Kraepelin had a modern vision of affective illness. He hypothesized that affective recurrences arose from enduring dispositions of depressive, cyclothymic, irritable, or 'manic' types. These dispositions appeared as 'temperaments' in English translations of his work. In the extreme, such temperamental gloominess or mo...
journal_title:Journal of affective disorders
pub_type: 杂志文章,评审
doi:10.1016/s0165-0327(00)00347-5
更新日期:2001-01-01 00:00:00
abstract::Recent advances in our understanding of both short- and long-term therapeutic interventions for depressive disorders have necessitated greater precision in defining appropriate therapeutic interventions. While these remarkable changes in treatment have been based on the introduction of newer antidepressant agents, the...
journal_title:Journal of affective disorders
pub_type: 杂志文章,评审
doi:10.1016/s0165-0327(00)00357-8
更新日期:2001-01-01 00:00:00
abstract::Electrodermal hyporeactivity in the anticipation of aversive stimuli is a highly reliable correlate of diagnosed psychopathy and undersocialized aggressive conduct disorder (UACD), and it has been interpreted as reflecting a weak behavioral inhibition system (BIS) as conceptualized in Gray's work (e.g., in: Royce, J.R...
journal_title:Journal of affective disorders
pub_type: 杂志文章,评审
doi:10.1016/s0165-0327(00)00336-0
更新日期:2000-12-01 00:00:00
abstract:BACKGROUND:Previous studies have demonstrated a blunted beta adrenoceptor-linked protein kinase A (PKA) response in the 900xg supernatant fraction of human fibroblasts cultured from patients with major depression. RESULTS:Results of the present studies demonstrate a significant reduction in the B(max) value of [3H]cyc...
journal_title:Journal of affective disorders
pub_type: 杂志文章
doi:10.1016/s0165-0327(99)00190-1
更新日期:2000-12-01 00:00:00
abstract:BACKGROUND:INN 00835 is a synthetic pentapeptide with a potential for rapid onset of action as an antidepressant. Its efficacy was investigated in a pilot study in patients diagnosed with major depression. METHODS:Fifty two patients received either active drug - INN 00835 (26 patients) - or placebo (26 patients), subc...
journal_title:Journal of affective disorders
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1016/s0165-0327(99)00187-1
更新日期:2000-12-01 00:00:00
abstract::The authors made a follow-up study among 118 depressive patients. The follow-up period was 11 years (mean 7.8 years). They have used the operational criteria elaborated by Lee and Murray. The suicide rate was 2.54%, calculated for annual average per 100000 inhabitants is 231.5. This figure is close to ten times higher...
journal_title:Journal of affective disorders
pub_type: 杂志文章
doi:10.1016/s0165-0327(99)00168-8
更新日期:2000-11-01 00:00:00
abstract:BACKGROUND:Previously published data show large differences between euthymic Israeli adult bipolar patients and US normative data on several measures of psychological functioning as assessed with a sensitive projective measure (Rorschach Inkblot Test). The current study examines the Rorschach performance of healthy off...
journal_title:Journal of affective disorders
pub_type: 杂志文章
doi:10.1016/s0165-0327(99)00148-2
更新日期:2000-09-01 00:00:00
abstract:BACKGROUND:Major depression with high levels of anxiety (anxious depression) is a common subtype of depression associated with greater psychosocial impairment and poorer response to antidepressant treatment. It is unclear whether in this population there are differences in efficacy or tolerability across selective sero...
journal_title:Journal of affective disorders
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1016/s0165-0327(99)00131-7
更新日期:2000-08-01 00:00:00
abstract:BACKGROUND:Seasonal variations in mood (seasonality) appear to be entrained to light, a physical zeitgeber. We hypothesised that people high in seasonality may be responsive to a range of zeitgebers, because of greater mood variability. We investigated whether the moods of people high in seasonality were more strongly ...
journal_title:Journal of affective disorders
pub_type: 杂志文章
doi:10.1016/s0165-0327(99)00122-6
更新日期:2000-07-01 00:00:00
abstract:BACKGROUND:Conflicting results in genetic studies of bipolar disorders may be due to the clinical and genetic heterogeneity of the disease. Age at onset of bipolar disorders may be a key indicator for identifying more homogeneous clinical subtypes. We tested whether early onset and late onset bipolar illness represent ...
journal_title:Journal of affective disorders
pub_type: 杂志文章
doi:10.1016/s0165-0327(99)00111-1
更新日期:2000-06-01 00:00:00